FOXP3, phosphorylated

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q9BZS1

Isotype

IgG

Grade

Affinity Purified

Applications

DB E

Crossreactivity

Accession #

NP_054728

Gene ID

50943

Gene #

IPEX

Shipping Temp

Blue Ice

Storage Temp

-20°C

FOXP3, IPEX, Forkhead box protein P3, Scurfin

The protein is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.

Applications

Suitable for use in Dot Blot, ELISA

Recommended Dilution

ELISA: 1:1,000 Dot blot 1:500

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Phospho-FOXP3-S418 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding S418 of human FOXP3.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Human

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)|Ganguly, S., et al. J. Invest. Dermatol. 130(4):1013-1022(2010)|Jung, D.J., et al. J. Biol. Chem. 285(11):7995-8002(2010)