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019102 (S,S)-Palonosetron-d3 Hydrochloride CAS:

Specifications
References
Grade
Highly Purified
Molecular Formula
C19H22D3ClN2O
Molecular Weight
335.89
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one-d3 Hydrochloride; Aloxi-d3; Onicit-d3; RS-25259-197-d3;

Serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

Form
White Solid
Melting Point
>297-299°C
Solubility
DMSO, Methanol
References
Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
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