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022861 VE 821 CAS: 1232410-49-9

Specifications
References
CAS Number
1232410-49-9
Grade
Highly Purified
MDL Number
MFCD19443686
Molecular Formula
C₁₈H₁₆N₄O₃S
Molecular Weight
368.41
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-2-pyrazinecarboxamide

VE 821 is a potent and selective inhibitor of DNA damage response kinase, ATR. VE 821 functions to disrupt DNA damage repair system of tumor cells, limiting their abilities for further growth.

Synonyms
3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-2-pyrazinecarboxamide
CAS Number
1232410-49-9
Molecular Formula
C₁₈H₁₆N₄O₃S
Molecular Weight
368.41
Appearance
Supplied as a yellow solid.
Melting Point
247-249°C
Solubility
Chloroform (Slightly), DMSO (Slightly)
Storage and Stability
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
1. Finlay, M., et al.: Bioorg. Medn. Chem. Letters., 22, 5352 (2012).
USBio References
No references available
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