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045047 MS-1020 CAS: 1255516-86-9

Specifications
References
CAS Number
1255516-86-9
Grade
Highly Purified
Molecular Formula
C21H18N2O3
Molecular Weight
346.4
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C/-20°C
1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide

Selective JAK3 inhibitor. Blocks STAT signaling. Inducer of apoptosis via down-regulation of anti-apoptotic gene expression.

Synonyms
1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide; 2-​Naphthalenecarboxami​de
CAS No
1255516-86-9
Molecular Weight
346.4
Molecular Formula
C21H18N2O3
Solubility
DMSO (at least 5mg/ml).
Appearance
Supplied as a white to off-white solid.
Purity
≥95% (NMR)
Storage and Stability
Store at -20°C. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. MS-1020 is a novel small molecule that selectively inhibits JAK3 activity: B.H. Kim, et al.; Br. J. Haematol. 148, 132 (2010)
USBio References
No references available
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