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233070 4-Chloro-L-Phenylalanine (L-Phe(4-Cl)-OH) CAS: 14173-39-8

Specifications
CAS Number
14173-39-8
Grade
Highly Purified
MDL Number
MFCD00063065
Molecular Formula
C₉H₁₀NO₂Cl
Molecular Weight
199.6
EU Commodity Code
38220090
UN DOT Shipping
UN2811 PGIII
Shipping Temp
RT
Storage Temp
4°C
L-Phe(4-Cl)-OH; p-Chloro-L-phenylalanine; H-Phe(4-Cl)-OH; (S)-2-Amino-3-(4-chlorophenyl)propionic acid

4-Iodo-L-phenylalanine is an unlabeled amino acid that has been shown to inhibit the protein synthesis of cancer cells. It binds to the thrombin receptor and inhibits the activation of proteases, thereby inhibiting cancer cell growth. 4-Iodo-L-phenylalanine also inhibits translation by binding to the ribosome during the translation process and binding to the hydroxyl group on a mRNA molecule during transcription. This inhibition leads to a decrease in protein synthesis and cell proliferation.

Synonyms
L-Phe(4-Cl)-OH; p-Chloro-L-phenylalanine; H-Phe(4-Cl)-OH; (S)-2-Amino-3-(4-chlorophenyl)propionic acid
CAS No
14173-39-8
Molecular Formula
C₉H₁₀NO₂Cl
Molecular Weight
199.60
Purity (HPLC)
≥99%
Solubility
1mM in 2ml Acetic acid/H2O
Appearance
White to off-white powder
Melting Point
220-223°C
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
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