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C5840-98 Clindamycin Hydrochloride CAS: 21462-39-5

Specifications
References
CAS Number
21462-39-5
Grade
Highly Purified
Molecular Formula
C18H34Cl2N2O5S
Molecular Weight
461.44
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
-20°C
(7S)-7-Chloro-7-deoxylincomycin hydrochloride; (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-a-D-galacto-octopyranoside

Clindamycin is a lincosamide antibiotic. It is usually used to treat infections with anaerobic bacteria, but can also be used to treat some protozoal diseases, such as malaria. It is a common topical treatment for acne and can be useful against some methicillin-resistant Staphylococcus aureus (MRSA) infections.[1] The most severe common adverse effect of clindamycin is Clostridium difficile-associated diarrhea (the most frequent cause of pseudomembranous colitis). Although this side effect occurs with almost all antibiotics, including beta-lactam antibiotics, it is classically linked to clindamycin use.[2]

Synonyms
(7S)-7-Chloro-7-deoxylincomycin hydrochloride; (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-a-D-galacto-octopyranoside
CAS No
21462-39-5
Molecular Formula
C18H34Cl2N2O5S
Molecular Weight
461.44
Appearance
Supplied as a white powder.
Potency
≥860ug/mg
Water
≤5%
Storage and Stability
Powder may be stored at -20°C. Stable for 6 months at -20°C. Hygroscopic. Store under inert atmosphere.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Daum RS (2007). "Clinical practice. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus". N Engl J Med 357(4):380-90. doi:10.1056/NEJMcp070747. PMID 17652653. 2. Thomas C, Stevenson M, Riley TV (2003). "Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review". J Antimicrob Chemother 51(6):1339–50. doi:10.1093/jac/dkg254. PMID 12746372.
USBio References
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