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R1988-01 Reveromycin B CAS: 144860-68-4

Specifications
References
CAS Number
144860-68-4
Grade
Highly Purified
Molecular Formula
C36H52O11
Molecular Weight
660.8
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C

Reveromycin B is an much less active analogue of reveromycin A formed by rearrangement of the 6to6 spiroketal to a 5to6 spiroketal. Lacking much of the biological activity of reveromycin A, the reveromycin B is a useful negative control in resolving the mode of action of this class.

Purity: >90% by HPLC
Solubility: Soluble in ethyl acetate, ethanol, methanol, DMF or DMSO, avoid acidic conditions.
Related to: Reveromycin A, Reveromycin C, Reveromycin D
Source
Streptomyces sp.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities. Takahashi H. et al. J. |Antibiot. 1992, 45, 1414. |2. Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific |inhibitor Reveromycin A. Miyamoto Y. et al. J. Biol. Chem. 2002, 277, 28810.
USBio References
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