Aliskiren Hemifumarate CAS 173334-58-2

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001776 Aliskiren Hemifumarate CAS: 173334-58-2

Specifications

References

CAS Number

173334-58-2

Grade

Highly Purified

Molecular Formula

C32H55N3O8

Molecular Weight

609.79

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

(αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeneoctanamide Hemifumarate; CGP 60536; CGP60536B; Rasilez Hemifumarate; SPP 100; Tekturna Hemifumarate

An orally active, synthetic nonpeptide renin inhibitor. Antihypertensive.

Synonyms

(αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeneoctanamide Hemifumarate; CGP 60536; CGP60536B; Rasilez Hemifumarate; SPP 100; Tekturna Hemifumarate

CAS No

173334-58-2

Form

White Solid

Melting Point

96-101°C

Solubility

Methanol, Water

References

Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000), Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2002), Wood, J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2003), Grandman, A.H., et al.: Circulation, 111, 1012 (2005),