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003979 rac Biotin-d4 CAS: 1217850-77-5

Specifications
References
CAS Number
1217850-77-5
Grade
Highly Purified
Molecular Formula
C10H12D4N2O3S
Molecular Weight
248.34
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
rel-(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic Acid-d4; rac Vitamin B7-d4; Coenzyme R-d4; Factor S-d4; Lutavit H2-d4; Meribin-d4; NSC 63865-d4; Rovimix H2-d4

Growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue.

Synonyms
rel-(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic Acid-d4; rac Vitamin B7-d4; Coenzyme R-d4; Factor S-d4; Lutavit H2-d4; Meribin-d4; NSC 63865-d4; Rovimix H2-d4
CAS No
1217850-77-5
Molecular Formula
C10H12D4N2O3S
Molecular Weight
248.34
Purity
Chemical purity: 98%; Isotopic purity: 99%
Appearance
White to off-white solid
Solubility
DMSO, Methanol (Sparingly)
1H NMR (DMSO-d6)
Conforms to reference
Normalized Intensity
d0=0.04%; d1=0.08%; d2=0.09%; d3=2.73%; d4=97.07%.
Melting Point
226-229°C (dec.)
TLC Conditions
SiO2; Dichloromethane: Methanol: Acetic acid = 9: 1: 0.1; Visualized with AMCS and KMnO4; Single spot; Rf=0.3.
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Form
Off-White Solid
Melting Point
229-230°C (dec.)
Solubility
DMSO, Methanol
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942). 2. Traub, et al.: Nature, 178, 649 (1956). 3. Siegel, H., et al.: Experienta, 37, 789 (1981). 4. Vesely, D.L., Science, 216, 1329 (1982). 5. Hugues, M., et al.: Biochemistry, 31, 12 (1992),
USBio References
No references available
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