BLI 489 Hydrate CAS 623564-40-9

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004328 BLI 489 Hydrate CAS: 623564-40-9

Specifications

References

CAS Number

623564-40-9

Grade

Purified

MDL Number

MFCD22374169

Molecular Formula

C₁₃H₁₀N₃NaO₄S • xH₂O

Molecular Weight

327.29

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

(5R,6Z)-6-[(5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt Hydrate; WAY-185489

BLI-489 is a penem β-lactamase inhibitor, which has shown activity against class A, C, and D β-lactamases. BLI-489 is being tested in combination therapy for drug-resistant bacteria.

Synonyms

(5R,6Z)-6-[(5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt Hydrate

CAS Number

623564-40-9

Molecular Formula

C₁₃H₁₀N₃NaO₄S • xH₂O

Molecular Weight

327.29

Form

Yellow Solid

Purity

≥98%

Melting Point

>200°C (dec.)

Solubility

DMSO, Methanol

Pfizer Compound

References

Maiti, S., et al.: Curr. Med. Chem., 5, 441 (1998), Barnaud, G., et al.: Antimicrob. Agents Chemother., 48, 1040 (2004), Szabo, D., et al.: J. Clin. Microbiol., 43, 5058 (2005)