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004337 BMS 299897 CAS: 290315-45-6

Specifications
References
CAS Number
290315-45-6
Grade
Highly Purified
Molecular Formula
C24H21ClF3NO4S
Molecular Weight
511.94
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluorobenzenebutanoic Acid;

BMS 299897 is a known γ-secretase inhibitor that effectively reduces amyloid β-peptide (Aβ) in transgenic mice and guinea pigs. Studies have shown the possibility of using BMS 299897 in the treatments for Alzheimer’s patients.

References
Anderson, J.J., et al.: Biochem. Pharmacol., 69, 689 (2005); Zheng, M., et al.: Xenoiotica., 39, 544 (2009); Narlawar, R., et al.: Bioorg. Medn. Chem. Letters., 17, 176 (2007);
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