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005505 25-Hydroxyvitamin D3 (Calcifediol) CAS: 19356-17-3

Specifications
References
CAS Number
19356-17-3
Grade
Highly Purified
Molecular Formula
C₂₇H₄₄O₂
Molecular Weight
400.64
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
(3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-Hydroxycholecalciferol; 25-Hydroxyvitamin D; 25-Hydroxyvitamin D3; Calcidiol; Didrogyl; Hidroferol; Ro 8-8892

A metabolite of Vitamin D. The principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator.

Synonyms
(3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-Hydroxycholecalciferol; 25-Hydroxyvitamin D; 25-Hydroxyvitamin D3; Calcidiol; Didrogyl; Hidroferol; Ro 8-8892
CAS No
19356-17-3
Molecular Formula
C₂₇H₄₄O₂
Molecular Weight
400.64
Purity
≥95% (HPLC)
Appearance
White to Off-White Solid
Melting Point
105-108ºC
Solubility
Chloroform (Heated), Methanol (Slightly)
Atmosphere
Inert Gas
Method for Determining Identity
Proton NMR Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
SiO2; Dichloromethane: Methanol=9:1; Visualized with UV and KMnO4; Single Spot, Rf=0.75
Elemental Analysis
Calculated: %C: 80.94; %H: 11.07
Water Content (Karl Fischer)
As Reported
Specific Rotation (c=0.3, Chloroform)
As Reported
Storage and Stability
Long-term storage is recommended at -20°C under inert gas. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
All products should be handled by qualified personnel only, trained in laboratory procedures.
Purity
≥95% (HPLC)
Form
Supplied as a white to off-white solid
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Morii, et al.: Arch. Biochem. Biophys., 120, 513 (1967). 2. Blunt, et al.: Biochemistry, 7, 3317 (1968). 3. Liu, et al.: Science, 311, 1770 (2006)
USBio References
No references available
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