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005608 S-(-)-Carbidopa CAS: 28860-95-9

Specifications
References
CAS Number
28860-95-9
Grade
Highly Purified
Molecular Formula
C10H14N2O4
Molecular Weight
226.23
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
(αS)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic Acid; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinamic Acid; (S)-Carbidopa; 1-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid; Carbidopa; HMD; Hydrazino-α-methyldopa; L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic Acid; L-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic Acid; L-α-Methyl-β-(3,4-dihydroxyphenyl)-α-hydrazinopropionic Acid; L-α-Methyldopahydrazine; Lodosin; Lodosyn; MK 486; N-Aminomethyldopa; α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic Acid; α-Methyldopahydrazine;

(S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.

References
Henry, G.M. et al.: Psychosom. Med., 38, 95 (1976); Leguire, L.E. et al.: Invest. Ophthalmol. Vis. Sci. 34, 3090 (1993); Deleu, D. et al.: Naun. Schmied. Arch. Pharmacol. 348: 576 (1993);
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