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005957 C6 Ceramide-13C2,d2 CAS:

Specifications
References
Grade
Highly Purified
Molecular Formula
C2213C2H45D2NO3
Molecular Weight
401.63
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
N-Hexanoy-D-sphingosine-13C2,d2; N-Caproyl-D-sphingosine-13C2,d2; Caproyl Ceramide-13C2,d2;

A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.

Form
Off-White Solid
Melting Point
69-72°C
Solubility
Chloroform, Methanol
References
Dobrowsky, R.T., et al.: J. Biol. Chem., 268, 15523 (1993), Raines, M.A., et al.: J. Biol. Chem., 268, 14572 (1993), Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1994),
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