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005970 S-Cetirizine Dihydrochloride CAS: 163837-48-7

Specifications
References
CAS Number
163837-48-7
Grade
Highly Purified
Molecular Formula
C21H27Cl3N2O3
Molecular Weight
461.81
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
(S)-[2-[4-[(4-Chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid Dihydrochloride

A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.

Form
White Solid
Melting Point
189-194°C
Solubility
Water
References
De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)
USBio References
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