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006000 Chenodeoxycholic Acid-d5 (Major) CAS: 52840-12-7

Specifications
References
CAS Number
52840-12-7
Grade
Highly Purified
Molecular Formula
C24H35D5O4
Molecular Weight
397.6
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
(3α,5β,7α)-3,7-Dihydroxycholan-24-oic Acid-d5; (+)-Chenodeoxycholic Acid-d5; 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7α-diol-d5; Chenodeoxycholic Acid-d5; CDC-d5; Chendol-d5; Chenodiol-d5; Chenocol-d5; Fluibil-d5

Labeled Chenodiol (Chenodeoxycholic acid). A major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Facilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.

Synonyms (3α,5β,7α)-3,7-Dihydroxycholan-24-oic Acid-d5; (+)-Chenodeoxycholic Acid-d5; 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7α-diol-d5; Chenodeoxycholic Acid-d5; CDC-d5; Chendol-d5; Chenodiol-d5; Chenocol-d5; Fluibil-d5
CAS Number
52840-12-7
Molecular Formula
C24H35D5O4
Purity
≥97%
Appearance
White to pale yellow solid
Solubility
Chloroform (Slightly), Methanol (Slightly)
Method for Determining Identity
Proton NMR Spectroscopic and Mass Spectrometric analysis
Elemental Analysis
Calculated: %C: 72.50, %H: 10.15
Normalized Intensity
d0=0.00%, d1=1.02%, d2=0.00%, d3=0.21%, d4=6.54%, d5=82.43%, d6=9.28%, d7=0.53%
Ethyl Acetate
As Reported
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4ºC for 6 months after time of receipt.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972). 2. Iser, J.H., et al.: Drugs, 21, 90 (1981). 3. Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986)
USBio References
No references available
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