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006756 Chlorpheniramine N-Oxide Dihydrochloride CAS:

Specifications
References
Grade
Highly Purified
Molecular Formula
C16H21Cl3N2O
Molecular Weight
363.71
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine N-Oxide Dihydrochloride

Major metabolite of Chlorpheniramine.

Atmosphere
Inert gas
Melting Point
103-107°C
Solubility
DMSO, Methanol
Method for Determining Identity
Proton NMR (DMSO-d6) and MS
TLC Conditions
SiO2; Dichloromethane : Methanol : Ammonium Hydroxide (8 : 2 : 0.15). Visualized with UV and Ninhydrin (single spot; Rf=0.45).
Storage and Stability
Store at -20°C under inert atmosphere. Caution: Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Source
Synthetic
Purity
~98%
Form
Pale yellow solid
References
Cashman, J., et al.: J. Chromatogr. Biomed App., 532, 405 (1990), Kasuya, F., et al.: Xenobiotica, 21, 97 (1991), Fried, K., et al.: J. Pharm. Biomed. Anal., 27, 479 (2001),
USBio References
No references available
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