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007049 Cortisone CAS: 53-06-5

Specifications
References
CAS Number
53-06-5
Grade
Highly Purified
MDL Number
MFCD00003610
Molecular Formula
C21H28O5
Molecular Weight
360.44
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
4-Pregnene-17α,21-diol-3,11,20-trione; 17,21-Dihydroxy-pregn-4-ene-3,11,20-trione; 17-Hydroxy-11-dehydrocorticosterone; 17a-Hydroxy-11-dehydrocorticosterone; 11-Dehydro-17-hydroxycorticosterone;|Adrenalex; Compound E; Cortisate; Cortivite; Cortogen; Cortone; NSC 9703; Kendall’s Compound E; Reichstein’s Substance Fa

Cortisone is a steroid hormone that belongs to the group of glucocorticoids. It is used in the treatment of inflammatory conditions, such as infectious diseases and asthma. Cortisone has been shown to have anti-inflammatory effects and can be used for the treatment of these conditions. Cortisone inhibits adipose tissue development by suppressing the expression of lipogenic enzymes and genes, which are involved in lipid synthesis. Cortisone has also been shown to have potential as a biomarker for identification of inflammation and infection, with higher levels found in patients with active inflammation or infection.

Synonyms
4-Pregnene-17α,21-diol-3,11,20-trione; 17,21-Dihydroxy-pregn-4-ene-3,11,20-trione; 17-Hydroxy-11-dehydrocorticosterone; 17a-Hydroxy-11-dehydrocorticosterone; 11-Dehydro-17-hydroxycorticosterone; Adrenalex; Compound E; Cortisate; Cortivite; Cortogen; Cortone; NSC 9703; Kendall’s Compound E; Reichstein’s Substance Fa
CAS No
53-06-5
Molecular Formula
C21H28O5
Molecular Weight
360.44
Appearance
White to off-white powder
Purity
≥95%
Melting Point
223-228°C (dec.) (lit.)
Solubility
Acetone, DMSO, Ethanol, Methanol, Chloroform: Methanol (1:1): 50mg/ml
Solubility
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Honda, A., et al.: J. Biol. Chem., 268, 7759 (1993), Narko, K., et al.: J. Clin. Endocrinol. Metab., 86, 1765 (2001), Michael, A., et al.: Reproduction, 126, 425 (2003),
USBio References
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