Cyclizine Hydrochloride CAS 303-25-3

CAS Number

303-25-3

Grade

Highly Purified

MDL Number

MFCD00067334

Molecular Formula

C18H23ClN2

Molecular Weight

302.84

EU Commodity Code

38220090

UN DOT Shipping

UN2811 PGIII

Shipping Temp

Storage Temp

4°C

1-(Diphenylmethyl)-4-methylpiperazine Hydrochloride; Marezine Hydrochloride; Marzine; N-Benzhydryl-N'-methylpiperazine Monohydrochloride

Cyclizine is a piperazine derivative with anti-emetic activity that is useful in the prevention and treatment of nausea and vomiting associated with motion sickness. Antiemetic.

CAS No

303-25-3

Molecular Weight

302.84

Molecular Formula

C18H23ClN2

Loss on Drying

≤ 1.0%

Melting Point

291-293°C

Solubility

DMSO, Methanol

FT-IR Spectrum

Corresponds to assigned structure

Storage and Stability

Powder may be stored at 4C. Stable for 6 months.

Source

Synthetic

Purity

≥ 98%

Form

Supplied as a white to pale yellow crystalline powder

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Kuntzman, R., et al., J. Pharmacol. Exp. Ther., 158, 332 (1967)|2. Walker, R., et al., Eur. J. Pharm. Sci., 4, 301 (1996)|3. Dumasia, M., et al., Xenobiotica, 32, 795 (2002)