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007350 Cyclophosphamide-d4 CAS: 173547-45-0

Specifications
References
CAS Number
173547-45-0
Grade
Highly Purified
Molecular Formula
C7H11D4Cl2N2O2P
Molecular Weight
265.11
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
N,N-Bis(2-chloroethyl)tetrahydro-4,5-d2-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide; Cycloblastin-d4;Cyclostin-d4;Cytoxan-d4; Endoxan-d4; Genoxal-d4; Hexadrin-d4; Mitoxan-d4;NSC 26271-d4;

It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.

Form
White to Off-White Solid
Melting Point
41-45°C
Solubility
Alcohol, Benzene, Chloroform, Dioxane, Ethylene Glycol,
References
Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),
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