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007525 Dasatinib-d8 CAS:

Specifications
References
Grade
Highly Purified
Molecular Formula
C22H18D8ClN7O2S
Molecular Weight
496.05
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl-d8]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide; BMS-354825-d8;

A new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.

Form
Off-White to Light Tan Solid
Melting Point
259-262°C
Solubility
Dimethyl Sulfoxide, Methanol
References
Lombardo, L.J., et al: J. Med. Chem., 47, 6658 (2004), Shah, N. P., et al.: Science, 305, 399 (2004), O’Hare, T., et al.: Curr. Opin. Genet. Dev., 16, 92 (2006),
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