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008151 2'-Deoxy-6-thio Guanosine CAS: 789-61-7

Specifications
References
CAS Number
789-61-7
Grade
Highly Purified
Molecular Formula
C10H13N5O3S
Molecular Weight
283.31
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione; 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine; 2'-Deoxythioguanosine; 2'-Desoxy-6-thioguanosine; NSC 71261; TGdR; Thioguanine Deoxyriboside; β-Thioguanine Deoxyriboside;

Guanosine derivative with cancer chemotherapeutic properties. It is involved in the inhibition of human RNase H-mediated RNA cleavage from DNA-RNA duplexes via incorporation into DNA.

References
Momparler, R.L. et al.: Cancer Treat. Rep., 62, 135 (1978); Krynetskaia, N.F. et al.: Mol. Pharmacol., 56, 841 (1999);
USBio References
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