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008724 N-Desmethyl Trifluoperazine Dihydrochloride CAS: 4617-82-7

Specifications
References
CAS Number
4617-82-7
Grade
Highly Purified
Molecular Formula
C20H24Cl2F3N3S
Molecular Weight
466.39
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
Deshydroxyethyl Fluphenazine Dihydrochloride; 10-[3-(1-Piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine Dihydrochloride; 10-[3-(1-Piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine Dihydrochloride; Demethyltrifluoperazine Dihydrochloride; NSC 644575; QSS 5; SQ 10018

A metabolite of the antipsychotic drug Trifluoperazine (TFP). Trifluoperazine is a medication used to treat schizophrenia and anxiety by balancing dopamine levels in the brain, which helps regulate mood, behavior, and thoughts. Trifluoperazine blocks dopamine receptors in the brain and can also depress the release of hormones and affect basal metabolism, body temperature, wakefulness, and more.

Synonyms
Deshydroxyethyl Fluphenazine Dihydrochloride; 10-[3-(1-Piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine Dihydrochloride; 10-[3-(1-Piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine Dihydrochloride; Demethyltrifluoperazine Dihydrochloride; NSC 644575; QSS 5; SQ 10018
CAS No
4617-82-7
Molecular Formula
C20H24Cl2F3N3S
Molecular Weight
466.39
Appearance
Light beige solid
Purity
≥97%
1H NMR (CD3OD, DMSO-d6), 19F NMR (DMSO-d6),MS
Conforms to reference
TLC Conditions
SiO2; Dichloromethane : Methanol : Ammonium Hydroxide = 8 : 2 : 0.2; Visualized with UV and Ninhydrin; Single Spot, Rf = 0.60.
Melting Point
188 234°C
Elemental Analysis
(Found) %C: 49.55, %H: 5.22, %N: 8.54; (Calculated) %C: 51.50, %H: 5.16, %N: 9.01
Chloride
~14%
Solubility
DMSO (Slightly), Methanol (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. Hygroscopic. Inert Gas. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Mahju, M., et al.: Biochem. Pharmacol., 18, 2701 (1969),
USBio References
No references available
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