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010361 2,5-Dimethyl Celecoxib CAS: 457639-26-8|

Specifications
References
CAS Number
457639-26-8|
Grade
Highly Purified
Molecular Formula
C18H16F3N3O2S
Molecular Weight
395.4
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
4-[5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; |DMC;

A non-cyclooxygenase-2 inhibitor analog of Celecoxib. The celecoxib analog, 2,5-di-Me celecoxib (DMC), lacks COX-2 inhibitory activity but exhibits cytotoxic properties comparable to the COX-2 inhibitor Celecoxib.

References
Deckmann, K. et al.: Biochem. Pharmacol., 80, 1365 (2010); Virrey, J.J. et al.: Mol. Cancer. Therap., 9, 631 (2010); Chen, S. et al.: Leukemia Res., 34, 250 (2010);
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