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010954 rac-cis Dorzolamide CAS: 120279-37-0

Specifications
References
CAS Number
120279-37-0
Grade
Highly Purified
Molecular Formula
C₁₀H₁₇ClN₂O₄S₃
Molecular Weight
360.9
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
(4R,6S)-rel-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Monohydrochloride; cis-4-(Ethylamino)-5,6-dihydro-6-|methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Monohydrochloride; Dorzolamide Related Compound B USP; Dorzolamide Impurity B (EP) Hydrochloride; Dorzolamide EP Impurity B

rac-cis Dorzolamide is an impurity of Dorzolamide.

Synonyms
(4R,6S)-rel-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Monohydrochloride; cis-4-(Ethylamino)-5,6-dihydro-6- methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Monohydrochloride; Dorzolamide Related Compound B USP; Dorzolamide Impurity B (EP) Hydrochloride; Dorzolamide EP Impurity B
CAS No
120279-37-0 Cis: 120279-90-5 (Free Base)
Molecular Formula
C₁₀H₁₇ClN₂O₄S₃
Molecular Weight
360.9
Appearance
White to off-white powder
Purity
As reported
Melting Point
>250°C (dec.)
Solubility
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Casini, A., et al.: Bioorg. Med. Chem. Lett., 13, 841 (2003), Clare, B., et al.: Bioorg. Med. Chem., 13, 2197 (2005)
USBio References
No references available
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