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011201 Epirubicinol (Mixture of Diastereomers) CAS: 76155-56-1

Specifications
References
CAS Number
76155-56-1
Grade
Highly Purified
Molecular Formula
C27H31NO11
Molecular Weight
545.54
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
10-[(3-Amino-2,36,-trideoxy-α-L-arabino-hexopyranosyl)oxy]-8-[(1S)-1,2|-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-(8S,10S)-5,12-naphthacenedione Citrate; 13-Dihydroadriamycin Citrate

A metabolite of Epirubicin, a neoplasm inhibitor.

Synonyms
10-[(3-Amino-2,36,-trideoxy-α-L-arabino-hexopyranosyl)oxy]-8-[(1S)-1,2 -dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-(8S,10S)-5,12-naphthacenedione Citrate; 13-Dihydroadriamycin Citrate
CAS No 76155-56-1
Molecular Formula
C27H31NO11
Molecular Weight
545.54
Appearance
Dark Red Solid
Purity
≥95%d
Melting Point
>120°C (dec.)
Solubility
DMSO (Slightly)
Method for Determining Identity
Proton NMR (DMSO-d6) and Mass Spectrometric Analysis
TLC Conditions
C18; Isopropanol: Water: Ammonium Hydroxide = 8: 2: 0.2; Visualized with UV and Ninhydrin; Single spot, Rf=0.55
Elemental Analysis
%C: 56.51, %H: 5.92, %N: 2.37
Atmosphere
Inert gas
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Moisture Sensitive. Store under inert atmosphere.
References
1. Salvatorelli, E., et al.: J. Biol. Chem., 281, 10990 (2006). 2. Salvatorelli, E., et al.: J. Pharmacol. Exper. Ther., 320, 790 (2007). 3. Efferth, T., et al.: Clin. Cancer Res., 14, 2405 (2008)
USBio References
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