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011406 Estrone 3-Sulfate Sodium Salt CAS: 438-67-5

Specifications
References
CAS Number
438-67-5
Grade
Highly Purified
MDL Number
MFCD00070035
Molecular Formula
C18H21NaO5S
Molecular Weight
372.41
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, monosodium salt; Estra-1,3,5(10)-trien-17-one 3-(Sulfooxy) Sodium Salt; Estrone Sulfate Sodium Salt; Conestoral; Estrone Sodium Sulfate; Morestin; NSC 18313; Sodium Estrone-3-sulfate

Estrogen used in hormone replacement therapy.

Synonyms
3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, monosodium salt; Estra-1,3,5(10)-trien-17-one 3-(Sulfooxy) Sodium Salt; Estrone Sulfate Sodium Salt; Conestoral; Estrone Sodium Sulfate; Morestin; NSC 18313; Sodium Estrone-3-sulfate
CAS No
438-67-5
Molecular Formula
C18H21NaO5S
Molecular Weight
372.41
Appearance
White solid
Purity
≥95%
Melting Point
270-275˚C
Solubility
Methanol: ~20mg/ml, clear, colorless to faintly yellow
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
1. Kannel, W., et al.: J. Clin. Epidemiol., 44, 183 (1991)|2. Raisz, L., et al.: J. Clin. Endocrinol. Metab., 81, 37|3. Nakamura Y, et al. Steroid sulfatase and estrogen sulfotransferase in the atherosclerotic human aorta. Am J Pathol. 2003;163(4):1329-1339.|4. Duncan L, et al. Inhibition of estrone sulfatase activity by estrone-3-methylthiophosphonate: a potential therapeutic agent in breast cancer. Cancer Res. 1993;53(2):298-303.|4. Karakus E, et al. Estrone-3-Sulfate Stimulates the Proliferation of T47D Breast Cancer Cells Stably Transfected With the Sodium-Dependent Organic Anion Transporter SOAT (SLC10A6). Front Pharmacol. 2018;9:941. Published 2018 Aug 21.
USBio References
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