N- CAS 40004-08-8

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011462 N-(Ethoxycarbonylmethyl)piperazine CAS: 40004-08-8

Specifications

References

CAS Number

40004-08-8

Grade

Highly Purified

Molecular Formula

C8H16N2O2

Molecular Weight

172.22

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

1-Piperazineacetic Acid Ethyl Ester; 2-(Piperazin-1-yl)acetic Acid Ethyl Ester; 4-(Carboethoxymethyl)piperazine; Ethyl 1-piperazineacetate; Ethyl 1-Piperazinylacetate; Ethyl 2-(piperazin-1-yl)acetate; Ethyl 2-Piperazinoacetate; Ethyl Piperazinoacetate; N-(Carboethoxymethyl)piperazine; N-(Ethoxycarbonylmethyl)piperazine; Piperazin-1-ylacetic Acid Ethyl Ester; ||

N-(Ethoxycarbonylmethyl)piperazine is used in the preparation of aralkylpiperazine- and aryl-substituted hydrazines, particularly benzylpiperazineacetyl hydrazones of hydroxyaryl aldehydes, as selective inducers of apoptosis and activators of procaspases for use as anticancer agents.

Form

Clear Thick Oil

Solubility

Chloroform, Methanol

References

Nakagawara, A., et al.: Cancer Res., 57, 4578 (1997), Denault, J., et al.: J. Biol. Chem., 278, 34042 (2003), Traven, A., et al.: Cancer Cell, 5, 107 (2004), Becattini, B., et al.: Chem. Biol., 11, 389 (2004),