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012713 Galacto-PUGNAc CAS: 1145878-98-3

Specifications
References
CAS Number
1145878-98-3
Grade
Purified
Molecular Formula
C₁₅H₁₉N₃O₇
Molecular Weight
353.33
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
2-(Acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-galactonimidic Acid δ-Lactone; Gal-PUGNAc

Galacto-PUGNAc is a highly selective inhibitor for β-hexosaminidases HEXA and HEXB is cell-permeable. Galacto-PUGNAc is able to modulate the activity of HEXA and HEXB in tissue culture, increasing ganglioside GM2 levels in neuroblastoma cells.

Synonyms
2-(Acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-galactonimidic Acid δ-Lactone; Gal-PUGNAc;
CAS No
1145878-98-3
Molecular Formula
C₁₅H₁₉N₃O₇
Molecular Weight
353.33
Purity
≥90%
Appearance
White to off-white solid
Solubility
DMSO (Slightly), Methanol (Slightly)
Method for Determining Identity
Proton NMR Spectroscopic and Mass Spectrometric Analysis
Melting Point
>145°C (dec.) (lit)
Elemental Analysis
As Reported
Specifc Rotation (c=0.1, Methanol)
As Reported
Ethyl Acetate Content
~4.1%
Atmosphere
Inert gas
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20ºC for 6 months after time of receipt. Hygroscopic. Store under inert atmosphere
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards
 All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Stubbs, K.A. et al.: Angew. Chem. Int. Ed., 48:1300 (2009)
USBio References
No references available
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