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012980 GSK 1059615 CAS: 1356195-42-0

Specifications
References
CAS Number
1356195-42-0
Grade
Highly Purified
Molecular Formula
C18H11N3O2S
Molecular Weight
333.36
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione;

GSK 1059615 is a potent inhibitor of PI 3-kinase α (PI3Kα). GSK 1059615 inhibits proliferation in BT474 cells and attenuates MAPK signaling.

References
Saadia, et al.: Clin. Cancer Res., 15, 3029 (2009), Knight, et al.: ACS Med. Chem. Lett., 1, 39 (2010),
USBio References
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