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013518 Hydroxy Bosentan-d4 CAS: 1065472-91-4

Specifications
References
CAS Number
1065472-91-4
Grade
Highly Purified
Molecular Formula
C27H25D4N5O7S
Molecular Weight
571.64
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d4; Ro 48-5033-d4

A labeled analogue of the active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.

Form
White Solid
Melting Point
124-127°C
Solubility
Methanol
References
Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)
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