10-Hydroxy Camptothecin-d5 CAS 1330277-66-1

CAS Number

1330277-66-1

Grade

Highly Purified

Molecular Formula

C20H11D5N2O5

Molecular Weight

369.38

EU Commodity Code

38220090

UN DOT Shipping

UN1544 PGIII

Shipping Temp

Storage Temp

-20°C

(4S)-4-(Ethyl-d5)-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (S)-10-Hydroxycamptothecin-d5; Hydroxycamptothecin-d5; NSC 107124-d5;

A labeled Camptothecin derivative; a topoisomerase inhibitor for cancer therapy.

Synonyms: (4S)-4-(Ethyl-d5)-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (S)-10-Hydroxycamptothecin-d5, Hydroxycamptothecin-d5, NSC 107124-d5

CAS No

1330277-66-1 Unlabeled: 19685-09-7

Molecular Formula

C20H11D5N2O5

Purity

≥95%

Appearance

Dark Green Solid

Solubility

DMSO (Slightly), Methanol (Slightly)

Melting Point

>216ºC (dec.)

Method for Determining Identity

Proton NMR and Mass Spectrometric Analysis

TLC Conditions

SiO2; Dichloromethane: Methanol = 8:2. Visualized with UV, KMnO4 and Naked Eye: Rf = 0.75.

Elemental Analysis

Calculated: %C;: 65.03, H: 4.37, N: 7.58

Storage and Stability

May be stored at RT for short-term only. Long-term storage is recommended at -20ºC for 6 months after receipt. Hygroscopic.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards

All products should be handled by qualified personnel only, trained in laboratory procedures.

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013539 10-Hydroxy Camptothecin-d5 CAS: 1330277-66-1

CAS Number

Grade

Molecular Formula

Molecular Weight

EU Commodity Code

UN DOT Shipping

Shipping Temp

Storage Temp

(4S)-4-(Ethyl-d5)-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (S)-10-Hydroxycamptothecin-d5; Hydroxycamptothecin-d5; NSC 107124-d5;

References

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