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014416 7-(2-Hydroxypropyl)guanine CAS: 56247-84-8

Specifications
References
CAS Number
56247-84-8
Grade
Highly Purified
Molecular Formula
C8H11N5O2
Molecular Weight
209.21
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
2-Amino-1,7-dihydro-7-(2-hydroxypropyl)-6H-purin-6-one; N7-(2-Hydroxypropyl)guanine;

A major adduct from alkylation of DNA by the genotoxic carcinogen, propylene oxide. Molecular dosimetry studies are used to find the amount present in tissues of F344 rats after inhalation exposure to propylene oxide

Form
Pale Beige Solid
Melting Point
>300°C
Solubility
DMSO
References
Rios-Blanco, M.N. et al.: Carcinogen., 24, 1233 (2003); Segerback, D. et al.: Chem.-Biol. Inter., 115, 229 (1998);
USBio References
No references available
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