N-Isobutyrylglycine CAS 15926-18-8

CAS Number

15926-18-8

Grade

Highly Purified

Molecular Formula

C6H11NO3

Molecular Weight

145.16

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

N-(2-methyl-1-oxopropyl)glycine; N-Isobutyrylglycine; (isobutyrylamino)acetic acid

N-Isobutyrylglycine detection is a useful diagnostic tool in the diagnosis of many organic acidemias and mitochondrial fatty acid β-oxidation defects. N-Isobutyrylglycine detection is also used in the diagnosis of isobutyryl-CoA dehydrogenase deficiency.

Synonyms

N-(2-methyl-1-oxopropyl)glycine; N-Isobutyrylglycine

CAS No

15926-18-8

Molecular Weight

145.16

Molecular Formula

C6H11NO3

Appearance

White to off-white solid

Purity

≥95%

Melting Point

100-102°C (lit)

Solubility

DMSO (Sparingly, Heated), Methanol (Slightly)

Method for Determining Identity

Proton NMR, C NMR and Mass Spectrometric Analysis

Elemental Analysis

As Reported

Isopropanol Content

As Reported

Storage and Stability

Powder is stable for 6 months after receipt at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

1. Costa, C. G. et al.: J. Pharmac. Biomed. Anal., 21, 1215 (2000). 2. Bonafe, L. et al.: Mol. Gen. Metab., 69, 311 (2000). 3. Sass, J. et al.: J. Inher. Metab. Dis., 27, 741 (2004);