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015396 KML-29 CAS: 1380424-42-9

Specifications
References
CAS Number
1380424-42-9
Grade
Highly Purified
Molecular Formula
C24H21F6NO7
Molecular Weight
549.42
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic Acid 2,2,2-Trifluoro-1-(trifluoromethyl)ethyl Ester; 1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(Bis(benzo[d][1,3]dioxol-5-yl)(hydroxy)methyl)piperidine-1-carboxylate; KML29;

KML-29 is an extremely specific monoacylglycerol lipase (MAGL) inhibitor. KML-2 should be useful to distinguish between actions of 2-arachidonoyl glycerol (an endogenous ligand of cannabinoid receptors that is deactivated by MAGL) and anandamide, another endocannabinoid.

References
Ueda, N. et al.: Chem. Biol., 19, 545 (2012);
USBio References
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