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015696 LPYFD-NH2 Trifluoroacetic Acid Salt CAS:

Specifications
References
Grade
Highly Purified
Molecular Formula
C33H44N6O8•C2HF3O2
Molecular Weight
766.76
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
L-Leucyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-α-asparagine Trifluoroacetic Acid Salt; Leu-Pro-Tyr-Phe-Asp-NH2 TFA;

LPYFD-NH2 is a neuroprotective peptide that binds to amyloid beta (Aβ). LPYFD-NH2 protects neurons against toxic effects of Aβ (1-42) in vitro and in vivo. LPYFD-NH2 is a potential therapeutic in the treatment of Alzheimer's Disease.

Form
White SOlid
Melting Point
>185°C (dec.)
Solubility
DMSO, Methanol
References
Wisniewski, T., et al.: Neurobiol. Dis., 4, 313 (1997), Wang, J., et al.: Exp. Neurol., 158, 328 (1999), Dahlgren, K., et al.: J. Biol. Chem. 277, 32046 (2002), Forman, M., et al.: Neurology, 68, 757 (2007),
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