Lubiprostone CAS 136790-76-6

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015698 Lubiprostone CAS: 136790-76-6

Specifications

References

CAS Number

136790-76-6

Grade

Highly Purified

Molecular Formula

C₂₀H₃₂F₂O₅

Molecular Weight

390.46

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid; Ru 0211

Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.

Synonyms

(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid; Ru 0211

CAS No

136790-76-6

Molecular Weight

390.46

Molecular Formula

C₂₀H₃₂F₂O₅

Melting Point

56-60°C

Solubility

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Form

White Solid

Storage and Stability

Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (2001), Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (2002), Coremans, G., et al.: Digestion, 67, 82 (2003),