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015990 Mesna CAS: 19767-45-4

Specifications
References
CAS Number
19767-45-4
Grade
Highly Purified
Molecular Formula
C2H5NaO3S2
Molecular Weight
164.18
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
2-Mercaptoethanesulfonic Acid

Mesna reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumor activity of antineoplastic drugs. This medication is used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.

Form
White to Off-White Solid
Melting Point
>240°C dec.
Solubility
Water
References
Tekeres, M., et al.: Clin. Ther., 4, 56 (1981), Brock, N., et al.: Eur. J. Cancer Clin Oncol., 18, 1377 (1982), James, C.A., et al.: Br. J. Clin. Pharmacol., 23, 561 (1987), Schoenike, S.E., et al.: Clin. Pharm., 9, 179 (1990),
USBio References
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