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017695 MK-0822 CAS: 603139-19-1

Specifications
References
CAS Number
603139-19-1
Grade
Highly Purified
Molecular Formula
C25H27F4N3O3S
Molecular Weight
525.56
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
N-(1-cyanocyclopropyl)-4-fluoro-N2-{(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl}-L-leucinamide, Odanacatib

MK-0822 is a newly developed bone-targeting dual action pro-drug for osteoporosis and bone metastasis. It is also an inhibitor of cathepsin K, an enzyme involved in bone resorption.

References
Arns, S., et al.: Bioorg. Medn. Chem., 20, 2131 (2012); Cusick, T., et al., J. Bone. Mineral. Rsch., 27, 524 (2013);
USBio References
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