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017844 Montelukast Methyl Ketone CAS: 937275-23-5

Specifications
References
CAS Number
937275-23-5
Grade
Highly Purified
Molecular Formula
C₃₄H₃₂ClNO₃S
Molecular Weight
570.14
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
1-[[[(1R)-3-(2-Acetylphenyl)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]thio]methyl]cyclopropaneacetic Acid; Montelukast EP Impurity F; Montelukast USP Related Compound E; Montelukast Methylketone

Montelukast impurity. A leukotriene antagonist useful as anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agent.

Synonyms
1-[[[(1R)-3-(2-Acetylphenyl)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]thio]methyl]cyclopropaneacetic Acid; Montelukast EP Impurity F; Montelukast USP Related Compound E; Montelukast Methylketone
CAS No
937275-23-5
Molecular Formula
C₃₄H₃₂ClNO₃S
Molecular Weight
937275-23-5
Appearance
Pale yellow low melting solid
Purity
≥97%
NMR
Conforms to reference
MS
Conforms to reference
Elemental Analysis
%C: 70.85, %H: 5.72, %N: 2.38
Specific Rotation
+58.1° (c = 0.3, Chloroform)
Melting Point
56-61°C
Solubility
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 67, 17 (1989),
USBio References
No references available
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