ent-Naxagolide Hydrochloride CAS 100935-99-7

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018032 ent-Naxagolide Hydrochloride CAS: 100935-99-7

Specifications

References

CAS Number

100935-99-7

Grade

Highly Purified

Molecular Formula

C15H22ClNO2

Molecular Weight

283.79

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

-20°C

(4aS-trans)-3,4,4a,5,6,10b-Hexahydro-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-9-ol Hydrochloride; (-)-Propyl-9-hydroxynaphthoxazine Hydrochloride;(-)-PHNO

A dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug.

Form

Off-White to Light Beige Solid

Melting Point

273-275°C (dec.)

Solubility

DMSO, Methanol

References

Fujita, N., et al.: Brain Res., 333, 231 (1985), Weiss, F., et al.: Eur. J, Pharmacol., 337, 219 (1997), Wilson, A., et al.: J. Med. Chem., 48, 4153 (2005), Ginovart, N., et al.: J. Neurochem., 97, 1089 (2006), Willeit, M., et al.: Biol. Psychiatry, 59, 389 (2006),