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018138 Nilotinib-d3 CAS:

Specifications
References
Grade
Highly Purified
Molecular Formula
C28H19D3F3N7O
Molecular Weight
532.53
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
4-Methyl-N-[3-(4-(methyl-d3)-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide; AMN 107-d3; Tasigna-d3;

Labeled analog of Nilotinib (AMN1O7), which might be useful in treatment of chronic myelogenous leukemia.

Form
Off-White to Pale Yellow Solid
Melting Point
227-230°C
Solubility
DMSO
References
Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),
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