2-Oxo-Zoniporide, HCl CAS 372078-42-7

CAS Number

372078-42-7

Grade

Highly Purified

Molecular Formula

C17H17ClN6O2

Molecular Weight

372.81

EU Commodity Code

38220090

Shipping Temp

Storage Temp

-20°C

N-(Aminoiminomethyl)-5-cyclopropyl-1-(1,2-dihydro-2-oxo-5-quinolinyl)-1H-pyrazole-4-carboxamide Hydrochloride

2-Oxo-Zoniporide is an metabolite of Zoniporide, a potent and selective inhibitor of human sodium-hydrogen exchanger isoform1(NHE-1) and protects against cardiac ischemia-reperfusion injury.

Synonyms

N-(Aminoiminomethyl)-5-cyclopropyl-1-(1,2-dihydro-2-oxo-5-quinolinyl)-1H-pyrazole-4-carboxamide Hydrochloride

CAS No

372078-42-7 Free Base: 372078-43-8

Molecular Formula

C17H17ClN6O2

Molecular Weight

372.81

Purity (HPLC)

≥95%

Appearance

Pale yellow to light brown solid

Solubility

DMSO (Slightly), Methanol (Slightly, Heated)

Method for Determining Identity

Conforms to Structure Proton NMR Spectroscopic Analysis and Mass Spectrometric Analysis

TLC Conditions

SiO2; Dichloromethane: Methanol: Ammonium Hydroxide=8:2:0.1; Visualized with UV and KMnO4; Single spot, Rf=0.35

Elemental Analysis

Calculated: %C: 54.77, %H: 4.60, %N: 22.54

Storage and Stability

May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. Hygroscopic. Store under inert atmosphere.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Toxicity and Hazards

All products should be handled by qualified personnel only, trained in laboratory procedures.

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019032 2-Oxo-Zoniporide, HCl CAS: 372078-42-7

CAS Number

Grade

Molecular Formula

Molecular Weight

EU Commodity Code

Shipping Temp

Storage Temp

N-(Aminoiminomethyl)-5-cyclopropyl-1-(1,2-dihydro-2-oxo-5-quinolinyl)-1H-pyrazole-4-carboxamide Hydrochloride

References

USBio References

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