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019081 Palmitoyldocosahexaenoyl Phosphatidylcholine CAS: 59403-54-2

Specifications
References
CAS Number
59403-54-2
Grade
Highly Purified
MDL Number
MFCD00674327
Molecular Formula
C₄₆H₈₀NO₈P
Molecular Weight
806.1
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
(7R,12Z,15Z,18Z,21Z,24Z,27Z)-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphatriaconta-12,15,18,21,24,27-hexaen-1-aminium 4-Oxide; 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine; Palmitoyldocosahexaenoylphosphatidylcholine

Palmitoyldocosahexaenoyl phosphatidylcholine (PC-S) is a fatty acid with six double bonds. It has been shown to induce osteogenic genes in human macrophages and can be used as a potential therapeutic agent for the treatment of bone diseases. PC-S also has anti-inflammatory properties, which is due to its ability to inhibit secretory phospholipase A2 (sPLA2). PC-S is structurally similar to the polyunsaturated fatty acid linoleic acid and has been found to have reactive properties. PC-S may be used as an adjuvant therapy for cancer and other diseases, such as Alzheimer's disease. Clinical studies are currently being conducted.

Synonyms
(7R,12Z,15Z,18Z,21Z,24Z,27Z)-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphatriaconta-12,15,18,21,24,27-hexaen-1-aminium 4-Oxide; 1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine; Palmitoyldocosahexaenoylphosphatidylcholine
CAS No
59403-54-2
Molecular Formula
C₄₆H₈₀NO₈P
Molecular Weight
806.1
Appearance
Yellow to dark brown gel to waxy solid
Purity
≥95%
Solubility
Chloroform (Slightly), Methanol (Slightly)
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Zhao, S., et al.: J. Pharm. Biomed. Anal., 47,P156910
USBio References
No references available
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