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019160 PD-166866 CAS: 192705-79-6

Specifications
References
CAS Number
192705-79-6
Grade
Highly Purified
Molecular Formula
C20H24N6O3
Molecular Weight
396.44
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
4°C
N-[2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)

A novel potent ATP competitive pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors. An inhibitor of the basic fibroplast growth factor (bFGF).

Form
Off-White to Pale Yellow Solid
Purity: ~90%
Melting Point
291-293°C (dec.)
Solubility
DMSO, Methanol (Sparingly)
References
Zhu, X., et al.: Science, 251, 90 (1991), Davies, D.E., et al.: Biochem. Pharmacol., 51, 1101 (1996), Panek, R.L., et al.: J. Pharmacol. Exp. Ther., 286, 569 (1998), Iacoangeli, A., et al.: Biochimie, 82, 35 (2000),
USBio References
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