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019734 Pinocembrin CAS: 480-39-7

Specifications
References
CAS Number
480-39-7
Grade
Highly Purified
Molecular Formula
C15H12O4
Molecular Weight
256.25
EU Commodity Code
38220090
Shipping Temp
RT
Storage Temp
RT
(2S)-2,3-Dihydro-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one; (S)-2,3-dihydro-5,7-dihydroxy-2-phenyl-4H-1-benzopyran-4-one; (+)-Pinocembrin; (+)-Pinocoembrin; (2S)-Pinocembrin; 5,7-Dihydroxyflavanone; Dihydrochrysin; Galangin Flavanone; NSC 279005;

Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c.

References
Zhao, J. et al.: J. Ethnopharmacol., 120, 387 (2008); Liu, R. et al.: Brain Res., 1216, 104 (2008); Gao, M. et al.: Eur. J. Pharmacol., 591, 73 (2008);
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