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021356 Tenofovir Diphosphate Triethylamine Salt (mixture of diastereomers) CAS: Free Acid: 166403-66-3

Specifications
References
CAS Number
Free Acid: 166403-66-3
Grade
Highly Purified
Molecular Formula
C9H16N5O10P3•x(C6H15N)
Molecular Weight
447.17
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
Diphosphoric Acid Triethylamine Salt , Anhydride with [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]|methyl]phosphonic Acid Triethylamine Salt; PMPApp Triethylamine Salt

A metabolite of Tenofovir.

Synonyms
Diphosphoric Acid Triethylamine Salt , Anhydride with [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy] methyl]phosphonic Acid Triethylamine Salt; PMPApp Triethylamine Salt
CAS No
Free Acid: 166403-66-3
Molecular Formula
C9H16N5O10P3•x(C6H15N)
Molecular Weight
447.17
Appearance
Off-white to pale yellow gel or low-melting solid
Purity
≥96%
Melting Point
43-45°C
Solubility
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Storage and Stability
Store at -20°C. Very hygroscopic, under Inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Melting Point
As Reported
Solubility
As Reported
Atmosphere
Inert gas
Method for Determining Identity
Proton (D2O) NMR Spectroscopic and Mass Spectrometric Analysis
TLC Conditions
As Reported
Storage and Stability
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic. Store under inert atmosphere.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards:  All products should be handled by qualified personnel only, trained in laboratory procedures.
References
Hazra, R., et al.: Antimicrob. Agents Chemother., 48, 124 (2004), Piketty, C., et al.: Antivir. Ther., 11, 213 (2006), Molto, J., et al.: Ther. Drug Monit., 29, 648 (2007)
USBio References
No references available
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