S-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid CAS 74163-81-8

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021540 S-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid CAS: 74163-81-8

Specifications

References

CAS Number

74163-81-8

Grade

Highly Purified

MDL Number

MFCD00144533

Molecular Formula

C₁₀H₁₁NO₂

Molecular Weight

177.2

EU Commodity Code

38220090

Shipping Temp

Storage Temp

4°C

(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid; L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid; L-3-Carboxy-1,2,3,4-tetrahydroisoquinoline; L-Porretine

(S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid (Quinapril EP Impurity A) is a Quinapril intermediate.

Synonyms

(-)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid; L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid; L-3-Carboxy-1,2,3,4-tetrahydroisoquinoline; L-Porretine

Impurity

Quinapril EP Impurity A

CAS No

74163-81-8

Molecular Weight

177.2

Molecular Formula

C₁₀H₁₁NO₂

Melting Point

>225°C (dec.)

Solubility

Hot Water, Basic Water

Appearance

Supplied as an off-white solid.

Storage and Stability

Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

References

1. Cheng, S., et al.: Eur. J. Med. Chem., 44, 4904 (2009).|2. Brust, A., et al.: J. Med. Chem., 52, 6991 (2009).|3. Toussaint, M., et al.: Eur. Neuropsychopharmacol., 19, 504 (2009),