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021809 Thromboxane B2 CAS: 54397-85-2

Specifications
References
CAS Number
54397-85-2
Grade
Highly Purified
Molecular Formula
C20H34O6
Molecular Weight
370.48
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
8-(1-Hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic Acid Hemiacetal; (5Z,9α,13E,15S)9,11,15-Trihydroxythromboxa-5,13-dien-1-oic Acid; TXB2; (5Z)-7-[(2R,3S,4S)-Tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]-2H-pyran-3-yl]-5-heptenoic Acid;

An inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 11-dehydro TBX2 and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion.

Form
White Solid
Melting Point
85-87°C
Solubility
Chloroform
References
Needleman, P. et al.: Nature, 261, 558 (1976); Patrono, C. et al.: J Clin. Invest., 77, 590 (1986); Patrono, C. et al.: Adv. Prostaglandin Thromboxane Leukot. Res., 11, 493 (1983);
USBio References
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