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021985 Topotecan-d5 CAS: 1133355-98-2

Specifications
References
CAS Number
1133355-98-2
Grade
Highly Purified
Molecular Formula
C23H18D5N3O5
Molecular Weight
426.48
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
(4S)-10-[(Dimethylamino)methyl]-4-(ethyl-d5)-4,9-dihydroxy-1H-pyrano[3’,4’,6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-609669-d5; SKF-104864A-d5; Hycamtin-d5;

Labeled Topotecan. A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic.

Form
Yellow Solid
Melting Point
>200°C (dec.)
Solubility
DMSO, Methanol (Sparingly)
References
Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990), BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1991), Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1992),
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